Article
Heterozygous alpha 1-antitrypsin deficiency (PiSZ) in an adolescent with asthma.
Southern medical journal - 1 Oct 1996
Nuckton T J, Beckerman R C
Abstract excerpt
Although alpha 1-antitrypsin deficiency has been associated with obstructive lung disease in individuals possessing a homozygous phenotype (PiZZ), this association has not been as clearly documented in heterozygous individuals (PiMZ, PiMS, and PiSZ phenotypes). Information regarding the heterozygous adolescent population is particularly lacking, making the evaluation and treatment of such patients difficult. We...
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