[Homozygous alpha 1-antitrypsin deficiency. Lung changes in children and adolescents].

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Article

[Homozygous alpha 1-antitrypsin deficiency. Lung changes in children and adolescents].

Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde - 1 May 1993

Paul K, Niggemann B

Abstract excerpt

Homozygous alpha 1-antitrypsin deficiency can lead to pan-lobular emphysema early in adulthood. Based on own studies and a review of the literature the article dates up the knowledge about risk factors (especially smoking), the variable clinical pattern (relationship to bronchial hyperreactivity)...

Topics

Adolescent
Bronchial Hyperreactivity
Child
Genetic Testing
Homozygote
Humans
Lung Diseases, Obstructive
Lung Volume Measurements
Phenotype
Tobacco Smoke Pollution
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

Source

Open in PubMed

Identifiers

PMID: 8326958

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8326958-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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