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Article

[Homozygous alpha-1 antitrypsin deficiency (PiZZ) and bronchial asthma in childhood--is there a connection?].

Klinische Padiatrie - 1 Jan 2000

Niggemann B, Claussen M, Koepp P

Abstract excerpt

Ten children and adolescents (aged four to 21 years) with the homozygous form of alpha-1-antitrypsin deficiency (PiZZ) were investigated with regard to obstructive airway disease. Besides the recording of the history, tests of lung function and allergy tests were performed. It was shown that bronchial asthma occurred in three out of ten patients. However, we could not demonstrate any statistically significant...

Topics

Adolescent
Asthma
Child
Child, Preschool
Female
Homozygote
Humans
Immunoglobulin E
Lung Volume Measurements
Male
Phenotype
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

alpha 1-Antitrypsin

alpha 1-Antitrypsin Deficiency

Source

Identifiers

PMID: 1583859
DOI: 10.1055/s-2007-1025330

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1583859-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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