Article
Heterozygous alpha 1-antichymotrypsin and PiZ alpha 1-antitrypsin deficiency. Prevalence and clinical spectrum in asthmatic children.
Allergy - 1 Apr 1990
Lindmark B, Svenonius E, Eriksson S
Abstract excerpt
In a case-control study we compared the prevalence of heterozygous deficiency of two closely related anti-neutrophil protease inhibitors, alpha 1-antitrypsin and alpha 1-antichymotrypsin, in 172 consecutive children with asthma. In a cohort study the clinical spectrum and severity were compared. On the basis of family studies 5/172 (2.9%) were classified as heterozygotes for alpha 1-antichymotrypsin deficiency, a...
Topics
- Asthma
- Child
- Child, Preschool
- Cohort Studies
- Female
- Heterozygote
- Humans
- Male
- Phenotype
- Sweden
- alpha 1-Antichymotrypsin
- alpha 1-Antitrypsin Deficiency