Characterization of the genetic polymorphism of dihydrocodeine O-demethylation in man via analysis of urinary dihydrocodeine and dihydromorphine by micellar electrokinetic capillary chromatography.

doi:10.1016/0378-4347(95)00396-7

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Article

Characterization of the genetic polymorphism of dihydrocodeine O-demethylation in man via analysis of urinary dihydrocodeine and dihydromorphine by micellar electrokinetic capillary chromatography.

Journal of chromatography. B, Biomedical applications - 29 Mar 1996

Hufschmid E, Theurillat R, Wilder-Smith C H, Thormann W

Abstract excerpt

The genetic polymorphism of dihydrocodeine O-demethylation in man via analysis of urinary dihydrocodeine (DHC) and dihydromorphine (DHM) by micellar electrokinetic capillary chromatography is described. Ten healthy subjects which are known to be extensive metabolizers for debrisoquine ingested 60...

Topics

Codeine
Dihydromorphine
Electrophoresis, Capillary
Humans
Methylation
Micelles
Phenotype
Polymorphism, Genetic
Quinidine
Reference Values

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Identifiers

PMID: 8861655
DOI: 10.1016/0378-4347(95)00396-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8861655-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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