Article
Prenatal diagnosis of beta-thalassaemia mutations using the reverse dot blot technique.
The National medical journal of India - 1 Jan 2000
Muralitharan S, Srivastava A, Shaji R V, Mathai M, Srivastava V M, Dennison D, Lu C Y, Krishnamoorthy R
Abstract excerpt
BACKGROUND: Beta-thalassaemia is the most common genetic disorder among Indians and a number of mutations causing this disease have been reported. Since effective treatment of thalassaemia major is complicated and very expensive, prenatal diagnosis has become an important option for those at risk...
Topics
- Adult
- Female
- Globins
- Humans
- Mutation
- Nucleic Acid Hybridization
- Pregnancy
- Prenatal Diagnosis
- beta-Thalassemia