Article
Advances in molecular diagnosis of inherited hemoglobin disorders.
Current opinion in hematology - 1 Mar 1996
Sutcharitchan P, Embury S H
Abstract excerpt
Molecular diagnosis for inherited disorders of hemoglobin production has been driven largely by the need for improved prenatal diagnosis. In turn, DNA-based testing has engendered better methods of fetal sampling. The sensitivity of DNA-based testing was increased tremendously by the polymerase chain reaction. Currently there are numerous polymerase chain reaction-based methods for diagnosing specific mutant...
Topics
- Amniocentesis
- Chorionic Villi Sampling
- DNA
- Fetal Diseases
- Hemoglobinopathies
- Humans
- Molecular Biology
- Mutation
- Polymerase Chain Reaction