Article
Prenatal diagnosis of beta-thalassaemia: experience in a developing country.
Prenatal diagnosis - 1 Jan 1998
Saxena R, Jain P K, Thomas E, Verma I C
Abstract excerpt
We present our experience with the amplification refractory mutation system (ARMS) for the prenatal diagnosis of beta-thalassaemia in 415 pregnancies of 360 women. Five mutations of the beta-thalassaemia gene common in Asian Indians accounted for 89.2 per cent and rare mutations for 7.2 per cent of all mutant chromosomes, while 3.3 per cent of chromosomes remained uncharacterized. Identical mutations were present...
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