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Article

Synthetic transcripts of double-stranded Birnavirus genome are infectious.

1 Oct 1996

Abstract excerpt

We have developed a system for generation of infectious bursal disease virus (IBDV), a segmented double-stranded RNA virus of the Birnaviridae family, with the use of synthetic transcripts derived from cloned cDNA. Independent full-length cDNA clones were constructed that contained the entire coding and noncoding regions of RNA segments A and B of two distinguishable IBDV strains of serotype I. Segment A encodes...

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PMID: 8855321
DOI: 10.1073/pnas.93.20.11131

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