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Article

Different domains of the RNA polymerase of infectious bursal disease virus contribute to virulence.

PloS one - 1 Jan 2012

Nouën Cyril Le, Toquin Didier, Müller Hermann, Raue Rüdiger, Kean Katherine M, Langlois Patrick, Cherbonnel Martine, Eterradossi Nicolas

Abstract excerpt

BACKGROUND: Infectious bursal disease virus (IBDV) is a pathogen of worldwide significance to the poultry industry. IBDV has a bi-segmented double-stranded RNA genome. Segments A and B encode the capsid, ribonucleoprotein and non-structural proteins, or the virus polymerase (RdRp), respectively. Since the late eighties, very virulent (vv) IBDV strains have emerged in Europe inducing up to 60% mortality. Although...

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Identifiers

PMID: 22253687
DOI: 10.1371/journal.pone.0028064
PMCID: PMC3258228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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