Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of a Mutant Infectious Bursal Disease Virus That Does Not Cause Bursal Lesions

1 Apr 1998

Abstract excerpt

A reverse genetics system for birnavirus, based on synthetic transcripts of the infectious bursal disease virus (IBDV) genome, was recently developed (E. Mundt and V. N. Vakharia, Proc. Natl. Acad. Sci. USA 93:11131-11136, 1996). To study the function of the 17-kDa nonstructural (NS) protein in viral growth and pathogenesis, we constructed a cDNA clone of IBDV segment A in which the first and only initiation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Viral Infections and Immunology Research
Share to Virology and Viral Diseases
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9525581
DOI: 10.1128/jvi.72.4.2647-2654.1998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of a Mutant Infectious Bursal Disease Virus That Does Not Cause Bursal LesionsPMID 9525581Read ↗

Synthetic transcripts of double-stranded Birnavirus genome are infectious.Semantic proximity Read ↗

Nonstructural protein of infectious bursal disease virus inhibits apoptosis at the early stage of virus infection.Semantic proximity Read ↗

Generation of a novel attenuated IBDV vaccine strain by mutation of critical amino acids in IBDV VP5.Semantic proximity Read ↗

VP5 of infectious bursal disease virus is not essential for viral replication in cell cultureSemantic proximity Read ↗

Chimeras in noncoding regions between serotypes I and II of segment A of infectious bursal disease virus are viable and show pathogenic phenotype in chickens.Semantic proximity Read ↗

Molecular determinants of virulence, cell tropism, and pathogenic phenotype of infectious bursal disease virus.Semantic proximity Read ↗

Induction of apoptosis in vitro by the 17-kDa nonstructural protein of infectious bursal disease virus: possible role in viral pathogenesis.Semantic proximity Read ↗

Non-Lytic Egression of Infectious Bursal Disease Virus (IBDV) Particles from Infected CellsSemantic proximity Read ↗

Rescue of Very Virulent and Mosaic Infectious Bursal Disease Virus from Cloned cDNA: VP2 Is Not the Sole Determinant of the Very Virulent PhenotypeSemantic proximity Read ↗

The Full Region of N-Terminal in Polymerase of IBDV Plays an Important Role in Viral Replication and Pathogenicity: Either Partial Region or Single Amino Acid V4I Substitution Does Not Completely Lead to the Virus Attenuation to Three-Yellow Chickens.Semantic proximity Read ↗

Different domains of the RNA polymerase of infectious bursal disease virus contribute to virulence.Semantic proximity Read ↗

Genome Evolution of Two Genetically Homogeneous Infectious Bursal Disease Virus Strains During Passages in vitro and ex vivo in the Presence of a Mutagenic Nucleoside AnalogSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.