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Construction of an Influenza D Virus with an Eight-Segmented Genome

27 Oct 2021

Abstract excerpt

Influenza D virus (IDV) may cause the bovine respiratory disease complex, which is the most common and costly disease affecting the cattle industry. Previously, we revealed that eight segments could be actively packaged in its single virion, suggesting that IDV with the seven-segmented genome shows an agnostic genome packaging mechanism. Herein, we engineered an eight-segmented recombinant IDV in which the NS1 or...

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PMID: 34834971
DOI: 10.3390/v13112166

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