Article
A novel method for simultaneous high resolution identification of HLA-A, HLA-B, and HLA-Cw alleles.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1996
Arguello R, Avakian H, Goldman J M, Madrigal J A
Abstract excerpt
We describe a novel high resolution DNA based typing approach for HLA class I alleles, which identifies the recombinational motifs present in exons 2 and 3 of the HLA class I genes. Unique identification patterns for 201 known HLA-A, HLA-B, and HLA-Cw alleles were generated by the use of only 40...
Topics
- Alleles
- Base Sequence
- Cell Line
- DNA Primers
- Genes, MHC Class I
- Heterozygote
- Histocompatibility Antigens Class I
- Humans
- Oligonucleotide Probes
- Polymerase Chain Reaction
