An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo.

doi:10.1242/dev.117.2.807

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Article

An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo.

Development (Cambridge, England) - 1 Feb 1993

Wharton K A, Ray R P, Gelbart W M

Abstract excerpt

decapentaplegic (dpp) is a zygotically expressed gene encoding a TGF-beta-related ligand that is necessary for dorsal-ventral patterning in the Drosophila embryo. We show here that dpp is an integral part of a gradient that specifies many different cell fates via intercellular signalling. There i...

Topics

Animals
Cell Differentiation
Drosophila
Embryonic Induction
Gene Expression
Genes, Insect
Morphogenesis
Mutation
Phenotype
Zygote

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