Article
Transcription of multiple yeast ribosomal DNA genes requires targeting of UAF to the promoter by Uaf30.
Molecular and cellular biology - 1 Nov 2008
Hontz Robert D, French Sarah L, Oakes Melanie L, Tongaonkar Prasad, Nomura Masayasu, Beyer Ann L, Smith Jeffrey S
Abstract excerpt
Upstream activating factor (UAF) is a multisubunit complex that functions in the activation of ribosomal DNA (rDNA) transcription by RNA polymerase I (Pol I). Cells lacking the Uaf30 subunit of UAF reduce the rRNA synthesis rate by approximately 70% compared to wild-type cells and produce rRNA us...
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