Article
Human bladder carcinoma cell lines as indicators of oncogenic change relevant to urothelial neoplastic progression.
British journal of cancer - 1 Sept 1995
Rieger K M, Little A F, Swart J M, Kastrinakis W V, Fitzgerald J M, Hess D T, Libertino J A, Summerhayes I C
Abstract excerpt
Analysis of human tumour-derived cell lines has previously resulted in the identification of novel transformation-related elements and provided a useful tool for functional studies of different genes. To establish the utility of such cell lines as indicators of change relevant to urothelial cancer, we have characterised the expression of five genes (p53, MDM2, Rb, E-cadherin, APC) within a panel of human bladder...
Topics
- Base Sequence
- Cadherins
- Disease Progression
- Gene Expression
- Genes, Tumor Suppressor
- Humans
- Immunohistochemistry
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Proto-Oncogene Proteins