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Article

Molecular genetic analysis of exons 1 to 6 of the APC gene in non-polyposis familial colorectal cancer.

Clinical genetics - 1 Dec 1995

Joyce J A, Froggatt N J, Davies R, Evans D G, Trembath R, Barton D E, Maher E R

Abstract excerpt

Familial adenomatous polyposis coli is caused by constitutional mutations in the APC gene. The hallmark of familial adenomatous polyposis coli is the presence of numerous (> 100) colorectal polyps, but mutations in the 5' end of the APC gene have been associated with familial colorectal cancer without florid polyposis. Although familial adenomatous polyposis coli accounts for only a minority of familial...

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Identifiers

PMID: 8835324
DOI: 10.1111/j.1399-0004.1995.tb04113.x

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APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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