Article
Association study of BDNF and CNTF polymorphism to depression in non-demented subjects of the "VITA" study.
Journal of affective disorders - 1 Nov 2006
Grünblatt E, Hupp E, Bambula M, Zehetmayer S, Jungwirth S, Tragl K H, Fischer P, Riederer P
Abstract excerpt
BACKGROUND: Neurotrophic factors are known to play an important role in the survival and differentiation of many types of neurons during development. Both brain-derived neurotrophic factor (BDNF) and ciliary neurotrophic factor (CNTF) may act cooperatively in modulating the development and functioning of synapses. Both these neurotrophic factors were intensely investigated with regard to depression without...
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