Complement 4 locus II gene deletion and DQA1*0301 gene: genetic risk factors for IgA nephropathy and Henoch-Schönlein nephritis.

doi:10.1159/000189098

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Article

Complement 4 locus II gene deletion and DQA1*0301 gene: genetic risk factors for IgA nephropathy and Henoch-Schönlein nephritis.

Nephron - 1 Jan 1996

Jin D K, Kohsaka T, Koo J W, Ha I S, Cheong H I, Choi Y

Abstract excerpt

There have been several reports suggesting that the deficiency of complement 4 (C4) and/or deletion of C4 genes are the genetic risk factors in patients with IgA nephropathy (IgAN) and Henoch-Schönlein nephritis (HSN). In the current study, we tried to clarify the genetic structure of deleted C4...

Topics

Adult
Alleles
Complement C4
DNA
Female
Gene Deletion
Glomerulonephritis, IGA
HLA-DQ Antigens
HLA-DR Antigens
Humans
IgA Vasculitis
Male
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Risk Factors

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