Article
Association of HLA-DQw4 with IgA nephropathy in the Japanese population.
Nephron - 1 Jan 1991
Hiki Y, Kobayashi Y, Ookubo M, Obata F, Kashiwagi N
Abstract excerpt
We have studied HLA-A, B, DR and DQ phenotypes in 50 Japanese patients with IgA nephropathy. The antigen frequency of HLA-DQw4, which is known to be associated with DR4/Dw15 specificity, was increased in the patient group as well as in those of B35 and DR4. The increase of DQw4 (36.0%) was significantly different from that of national controls (corrected p less than 0.004).
Topics
- Adult
- Epitopes
- Female
- Glomerulonephritis, IGA
- HLA-DQ Antigens
- Humans
- Japan
- Male
- Phenotype