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Article

A tyrosyl-tRNA synthetase suppresses structural defects in the two major helical domains of the group I intron catalytic core.

Journal of molecular biology - 20 Sept 1996

Myers C A, Wallweber G J, Rennard R, Kemel Y, Caprara M G, Mohr G, Lambowitz A M

Abstract excerpt

The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase, the CYT-18 protein, functions in splicing group I introns by promoting the formation of the catalytically active structure of the intron RNA. The group I intron catalytic core is thought to consist of two extended helical domains, one formed by coaxial stacking of P5, P4, P6, and P6a (P4-P6 domain) and the other consisting of P8, P3, P7, and P9 (P3-P9...

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Identifiers

PMID: 8831782
DOI: 10.1006/jmbi.1996.0501

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A tyrosyl-tRNA synthetase suppresses structural defects in the two major helical domains of the group I intron catalytic core.PMID 8831782Read ↗

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