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Article

The Neurospora crassa CYT-18 protein C-terminal RNA-binding domain helps stabilize interdomain tertiary interactions in group I introns.

RNA (New York, N.Y.) - 1 Apr 2004

Chen Xin, Mohr Georg, Lambowitz Alan M

Abstract excerpt

The Neurospora crassa mitochondrial tyrosyl-tRNA synthetase (CYT-18 protein) promotes the splicing of group I introns by stabilizing the catalytically active RNA structure. To accomplish this, CYT-18 recognizes conserved structural features of group I intron RNAs using regions of the N-terminal nucleotide-binding fold, intermediate alpha-helical, and C-terminal RNA-binding domains that also function in binding...

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Identifiers

PMID: 15037773
DOI: 10.1261/rna.5212604
PMCID: PMC1370554

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Source receipt: pubmed, retrieved 7 Sept 2026.

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