The ability of beta-lactam antibiotics to select mutants with derepressed beta-lactamase synthesis from Citrobacter freundii.

doi:10.1093/jac/36.3.483

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Article

The ability of beta-lactam antibiotics to select mutants with derepressed beta-lactamase synthesis from Citrobacter freundii.

The Journal of antimicrobial chemotherapy - 1 Sept 1995

Stapleton P, Shannon K, Phillips I

Abstract excerpt

The ability of beta-lactam compounds to induce synthesis of the class C beta-lactamase of Citrobacter freundii was assessed both directly and indirectly, the latter by measurement of the different susceptibilities of strains with inducible and depressed beta-lactamase synthesis and those of a bet...

Topics

Anti-Bacterial Agents
Citrobacter freundii
Enzyme Induction
Microbial Sensitivity Tests
Mutation
beta-Lactamases
beta-Lactams

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