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Article

Origin and evolution of the AmpC beta-lactamases of Citrobacter freundii.

Antimicrobial agents and chemotherapy - 1 May 2002

Barlow Miriam, Hall Barry G

Abstract excerpt

To determine whether the widespread clinical use of beta-lactams has been selective for Citrobacter freundii-derived alleles of plasmid ampC genes, we generated a Bayesian consensus phylogeny of the published ampC sequences and compared the MICs of 16 beta-lactam antibiotics for Escherichia coli strains containing cloned copies of the C. freundii ampC alleles. We found that for the majority of compounds...

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Identifiers

PMID: 11959544
DOI: 10.1128/AAC.46.5.1190-1198.2002
PMCID: PMC127158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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