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Article

The identification, cloning and mutagenesis of a genetic locus required for lipopolysaccharide biosynthesis in Bordetella pertussis.

Molecular microbiology - 1 Jan 1996

Allen A, Maskell D

Abstract excerpt

Bordetella pertussis lipopolysaccharide (LPS) is biologically active, being both toxic and immunogenic. Using transposon mutagenesis we have identified a genetic locus required for the biosynthesis of LPS in B. pertussis, which has been cloned and sequenced. We have also identified equivalent loci in Bordetella bronchiseptica and Bordetella parapertussis and cloned part of it from B. parapertussis. The amino acid...

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Identifiers

PMID: 8821935
DOI: 10.1046/j.1365-2958.1996.354877.x

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