Article
Role of Bordetella O antigen in respiratory tract infection.
Infection and immunity - 1 Jan 2003
Burns Valorie C, Pishko Elizabeth J, Preston Andrew, Maskell Duncan J, Harvill Eric T
Abstract excerpt
Lipopolysaccharide (LPS), as the major surface molecule of gram-negative bacteria, interacts with the host in complex ways, both inducing and protecting against aspects of inflammatory and adaptive immunity. The membrane-distal repeated carbohydrate structure of LPS, the O antigen, can prevent antibody functions and may vary as a mechanism of immune evasion. Genes of the wbm locus are required for the assembly of...
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