Genetic basis for lipopolysaccharide O-antigen biosynthesis in bordetellae.

doi:10.1128/IAI.67.8.3763-3767.1999

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Article

Genetic basis for lipopolysaccharide O-antigen biosynthesis in bordetellae.

Infection and immunity - 1 Aug 1999

Preston A, Allen A G, Cadisch J, Thomas R, Stevens K, Churcher C M, Badcock K L, Parkhill J, Barrell B, Maskell D J

Abstract excerpt

Bordetella bronchiseptica and Bordetella parapertussis express a surface polysaccharide, attached to a lipopolysaccharide, which has been called O antigen. This structure is absent from Bordetella pertussis. We report the identification of a large genetic locus in B. bronchiseptica and B. parapertussis that is required for O-antigen biosynthesis. The locus is replaced by an insertion sequence in B. pertussis,...

Topics

Bordetella
Bordetella bronchiseptica
Chromosome Mapping
Cloning, Molecular
Mutation
O Antigens
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PMID: 10417135
DOI: 10.1128/IAI.67.8.3763-3767.1999
PMCID: PMC96651

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