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Article

Expression of FGF1 and FGFR1 in human melanoma tissues

1 Jun 1996

Abstract excerpt

Fibroblast growth factor 2 (FGF2) has been implicated in the pathogenesis of malignant melanoma (MM), but the role of other FGFs and their receptors (FGFRs) is not elucidated. To determine whether FGF1 and FGFR1 may be involved in MM growth in vivo, we have studied the expression of the FGF1 and FGFR1 genes in 77 fresh MM biopsy samples, using RT-PCR analysis. Samples of benign nevi, normal skin and carcinoma...

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PMID: 8819125
DOI: 10.1097/00008390-199606000-00005

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