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Article

Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes.

International journal of cancer - 1 Oct 1994

Rodeck U, Bossler A, Kari C, Humphreys C W, Györfi T, Maurer J, Thiel E, Menssen H D

Abstract excerpt

We report expression of the wt1 (Wilms' tumor) gene by cultured human melanoma cells. Using RNA polymerase chain reaction analysis, wt1 transcripts were detected in 7 of 9 melanoma cell lines but not in 5 normal melanocyte strains. In Northern blot analysis, steady-state wt1 mRNA levels were found in 2 of 4 melanoma lines but not in normal melanocytes. Sequence analysis of the wt1 cDNA expressed by melanoma cell...

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Identifiers

PMID: 7927908
DOI: 10.1002/ijc.2910590116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes.PMID 7927908Read ↗

Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth.Semantic proximity Read ↗

The Wilms tumour gene WT1 is expressed in murine mesoderm–derived tissues and mutated in a human mesotheliomaSemantic proximity Read ↗

The Wilms' tumor gene Wt1 is required for normal development of the retinaSemantic proximity Read ↗

RNA editing in the Wilms' tumor susceptibility gene, WT1.Semantic proximity Read ↗

Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors.Semantic proximity Read ↗

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.Semantic proximity Read ↗

Constitutive expression of the Wilms’ tumor gene WT1 inhibits the differentiation of myeloid progenitor cells but promotes their proliferation in response to granulocyte-colony stimulating factor (G-CSF)Semantic proximity Read ↗

msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation.Semantic proximity Read ↗

TRP‐1 expression correlates with eumelanogenesis in human pigment cells in cultureSemantic proximity Read ↗

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryoSemantic proximity Read ↗

The Wilms tumor suppressor-1 target gene podocalyxin is transcriptionally repressed by p53.Semantic proximity Read ↗

Functional properties of WT1.Semantic proximity Read ↗

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