Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Receptor binding site-deleted foot-and-mouth disease (FMD) virus protects cattle from FMD

1 Sept 1995

Abstract excerpt

Binding of foot-and-mouth disease virus (FMDV) to cells requires an arginine-glycine-aspartic acid (RGD) sequence in the capsid protein VP1. We have genetically engineered an FMDV in which these three amino acids have been deleted, producing a virus particle which is unable to bind to cells. Cattle vaccinated with these receptor binding site-deleted virions were protected from disease when challenged with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Viral Infections and Immunology Research
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7637023
DOI: 10.1128/jvi.69.9.5787-5790.1995

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Receptor binding site-deleted foot-and-mouth disease (FMD) virus protects cattle from FMDPMID 7637023Read ↗

Analysis of a Foot-and-Mouth Disease Virus Type A <sub>24</sub> Isolate Containing an SGD Receptor Recognition Site In Vitro and Its Pathogenesis in CattleSemantic proximity Read ↗

Foot-and-mouth disease virus: a long known virus, but a current threat.Semantic proximity Read ↗

Propagation of an attenuated virus by design: engineering a novel receptor for a noninfectious foot-and-mouth disease virus.Semantic proximity Read ↗

Foot and mouth disease virus: A reviewSemantic proximity Read ↗

Virus–Host Interactions in Foot-and-Mouth Disease Virus InfectionSemantic proximity Read ↗

Molecular Mechanisms of Immune Escape for Foot-and-Mouth Disease VirusSemantic proximity Read ↗

Immunogenicity and protective efficacy of 3A truncated negative marker foot-and-mouth disease virus serotype A vaccine.Semantic proximity Read ↗

Targeted Modification of the Foot-And-Mouth Disease Virus Genome for Quick Cell Culture AdaptationSemantic proximity Read ↗

Point mutations within the betaG-betaH loop of foot-and-mouth disease virus O1K affect virus attachment to target cells.Semantic proximity Read ↗

Cellular Receptors for Foot and Mouth Disease VirusSemantic proximity Read ↗

RGD sequence of foot-and-mouth disease virus isessential for infecting cells via the natural receptor but can be bypassed by anantibody-dependent enhancement pathway.Semantic proximity Read ↗

Animal-derived antigenic variants of foot-and-mouth disease virus type A12 have low affinity for cells in cultureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.