Article
Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus.
Proceedings of the National Academy of Sciences of the United States of America - 9 Jan 2018
Baggen Jim, Hurdiss Daniel L, Zocher Georg, Mistry Nitesh, Roberts Richard W, Slager Jasper J, Guo Hongbo, van Vliet Arno L W, Wahedi Maryam, Benschop Kimberley, Duizer Erwin, de Haan Cornelis A M, de Vries Erik, Casasnovas José M, de Groot Raoul J, Arnberg Niklas, Stehle Thilo, Ranson Neil A, Thibaut Hendrik Jan, van Kuppeveld Frank J M
Abstract excerpt
Acute hemorrhagic conjunctivitis (AHC) is a painful, contagious eye disease, with millions of cases in the last decades. Coxsackievirus A24 (CV-A24) was not originally associated with human disease, but in 1970 a pathogenic "variant" (CV-A24v) emerged, which is now the main cause of AHC. Initially, this variant circulated only in Southeast Asia, but it later spread worldwide, accounting for numerous AHC outbreaks...
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