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Article

Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes.

Molecular and cellular biology - 1 Feb 1990

Nadin-Davis S A, Nasim A

Abstract excerpt

We have further investigated the function of the ras1 and byr1 genes, which were previously shown to be critical for sexual differentiation in fission yeast cells. Several physiological similarities between strains containing null alleles of these genes supports the idea that ras1 and byr1 are functionally closely related. Furthermore, we have found that byr1 is allelic to ste1, one of at least 10 genes which...

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Identifiers

PMID: 2300054
DOI: 10.1128/mcb.10.2.549-560.1990
PMCID: PMC360835

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes.PMID 2300054Read ↗

byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype.Semantic proximity Read ↗

The Schizosaccharomyces pombe mra1 gene, which is required for cell growth and mating, can suppress the mating inefficiency caused by a deficit in the Ras1 activity.Semantic proximity Read ↗

Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe.Semantic proximity Read ↗

The ras1 function of Schizosaccharomyces pombe mediates pheromone-induced transcription.Semantic proximity Read ↗

Functional analysis of domains in the Byr2 kinase.Semantic proximity Read ↗

Genetic analysis of the sam mutations, which induce sexual development with no requirement for nutritional starvation in fission yeast.Semantic proximity Read ↗

Bob1, a Gim5/MM-1/Pfd5 homolog, interacts with the MAP kinase kinase Byr1 to regulate sexual differentiation in the fission yeast, Schizosaccharomyces pombe.Semantic proximity Read ↗

A novel gene, msa1, inhibits sexual differentiation in Schizosaccharomyces pombe.Semantic proximity Read ↗

Functional conservation between Schizosaccharomyces pombe ste8 and Saccharomyces cerevisiae STE11 protein kinases in yeast signal transduction.Semantic proximity Read ↗

Constitutive activation of the fission yeast pheromone-responsive pathway induces ectopic meiosis and reveals ste11 as a mitogen-activated protein kinase target.Semantic proximity Read ↗

Suppression of sorbitol dependence in a strain bearing a mutation in the SRB1/PSA1/VIG9 gene encoding GDP-mannose pyrophosphorylase by PDE2 overexpression suggests a role for the Ras/cAMP signal-transduction pathway in the control of yeast cell-wall biogenesis.Semantic proximity Read ↗

Complementation of byr1 in fission yeast by mammalian MAP kinase kinase requires coexpression of Raf kinase.Semantic proximity Read ↗

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