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Article

Epistasis and pleiotropy as natural properties of transcriptional regulation.

Theoretical population biology - 1 Feb 1996

Gibson G

Abstract excerpt

A statistical thermodynamic model of transcriptional regulation is employed to investigate the likely effects of genetic variation on the stabilization of gene expression. The model is tailored to empirical data on the control of transcription of the hunchback gene by the morphogen Bicoid during...

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Identifiers

PMID: 8813014
DOI: 10.1006/tpbi.1996.0003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8813014-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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