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Article

Hybrid incompatibility despite pleiotropic constraint in a sequence-based bioenergetic model of transcription factor binding.

Genetics - 1 Dec 2014

Tulchinsky Alexander Y, Johnson Norman A, Porter Adam H

Abstract excerpt

Hybrid incompatibility can result from gene misregulation produced by divergence in trans-acting regulatory factors and their cis-regulatory targets. However, change in trans-acting factors may be constrained by pleiotropy, which would in turn limit the evolution of incompatibility. We employed a...

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Share to Biological Evolution
Share to Gene Expression Regulation
Share to Hybridization, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mutation Rate

Share to Quantitative Trait, Heritable

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Share to Selection, Genetic

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Identifiers

PMID: 25313130
DOI: 10.1534/genetics.114.171397
PMCID: PMC4256777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25313130-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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