Article
Hypothermia inhibits human E-selectin transcription.
The Journal of surgical research - 1 Aug 1996
Haddix T L, Pohlman T H, Noel R F, Sato T T, Boyle E M, Verrier E D
Abstract excerpt
During endothelial cell activation, the formation and expression of E-selectin require transcriptional activation of the E-selectin gene, mediated by the coordinated action of several transcription factors and cis-acting elements in its 5'-flanking region. It is reported that in vitro hypothermia (25 degrees C) transiently inhibits transcriptional activation and surface expression of E-selectin as well as...
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