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Article

Inhibition of nuclear factor-kappaB-mediated adhesion molecule expression in human endothelial cells.

Circulation research - 23 Feb 1998

Lockyer J M, Colladay J S, Alperin-Lea W L, Hammond T, Buda A J

Abstract excerpt

The transcriptional regulatory protein nuclear factor-kappaB (NF-kappaB) participates in the control of gene expression of many modulators of the inflammatory and immune responses, including the adhesion molecules E-selectin and intercellular adhesion molecule-1 (ICAM-1). NF-kappaB is found in the cytoplasm complexed with its inhibitory protein IkappaB. On activation, IkappaB is phosphorylated and degraded,...

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PMID: 9486659
DOI: 10.1161/01.res.82.3.314

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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