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Article

Evidence for endocytosis of E‐selectin in human endothelial cells

1 Oct 1992

Abstract excerpt

E-selectin is an inducible adhesion molecule on endothelial cells. The internalization of this glycoprotein was investigated on tumor necrosis factor (TNF)-activated cultured human umbilical vein endothelial cells (HUVEC). Kinetics of intercellular adhesion molecule-1 (ICAM-1) were studied in parallel experiments. Internalization studies were performed with radioiodinated antibodies in an acid elution endocytosis...

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PMID: 1382989
DOI: 10.1002/eji.1830221009

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