Article
Glomerular-specific imprinting of the mouse gsalpha gene: how does this relate to hormone resistance in albright hereditary osteodystrophy?
Genomics - 1 Sept 1996
Williamson C M, Schofield J, Dutton E R, Seymour A, Beechey C V, Edwards Y H, Peters J
Abstract excerpt
The gene for alpha-stimulating guanine-nucleotide binding polypeptide, Gnas, has been considered as a candidate for the imprinting effects ascribed to distal mouse Chromosome (Chr) 2. Its human homologue (GNAS1) appears, from clinical and biochemical studies of patients with Albright hereditary o...
Topics
- Alleles
- Animals
- Chromosome Mapping
- Female
- GTP-Binding Protein alpha Subunits, Gs
- Gene Expression
- Genomic Imprinting
- Glomerular Mesangium
- Hormones
- Kidney
- Male
- Mice
- Mice, Inbred C3H
- Pseudohypoparathyroidism