Measles viruses with altered envelope protein cytoplasmic tails gain cell fusion competence.

doi:10.1128/JVI.72.2.1224-1234.1998

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Article

Measles viruses with altered envelope protein cytoplasmic tails gain cell fusion competence.

Journal of virology - 1 Feb 1998

Cathomen T, Naim H Y, Cattaneo R

Abstract excerpt

The cytoplasmic tail of the measles virus (MV) fusion (F) protein is often altered in viruses which spread through the brain of patients suffering from subacute sclerosing panencephalitis (SSPE). We transferred the coding regions of F tails from SSPE viruses in an MV genomic cDNA. Similarly, we c...

Topics

Amino Acid Sequence
Cell Fusion
Genome, Viral
HeLa Cells
Humans
Measles virus
Molecular Sequence Data
Mutation
Subacute Sclerosing Panencephalitis
Viral Fusion Proteins

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