Article
Glycoprotein-mediated biological properties of a host range mutant of Junin virus.
Research in virology - 1 Jan 2000
Scolaro L A, Damonte E B
Abstract excerpt
The biological properties mediated by the main envelope glycoprotein (GP1) of a mouse-attenuated mutant of Junin virus, named Cl67, were investigated in comparison with its parental strain XJCl3. In contrast to the parental strain, this mutant was unable to multiply in primary cultures of mouse embryo fibroblasts (MEFs). Impairment of Cl67 multiplication was associated with a lack of virus binding to MEF,...
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