Article
Yeast HOG1 MAP kinase cascade is regulated by a multistep phosphorelay mechanism in the SLN1-YPD1-SSK1 "two-component" osmosensor.
Cell - 20 Sept 1996
Posas F, Wurgler-Murphy S M, Maeda T, Witten E A, Thai T C, Saito H
Abstract excerpt
An osmosensing mechanism in the budding yeast (Saccharomyces cerevisiae) involves both a two-component signal transducer (Sln1p, Ypd1p and Ssk1p) and a MAP kinase cascade (Ssk2p/Ssk22p, Pbs2p, and Hog1p). The transmembrane protein Sln1p contains an extracellular sensor domain and cytoplasmic hist...
Topics
- Amino Acid Sequence
- Aspartic Acid
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- Cloning, Molecular
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Histidine
- Intracellular Signaling Peptides and Proteins
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Phenotype
- Phosphorylation