Article
Different members of the Sp1 multigene family exert opposite transcritional regulation of the long terminal repeat of HIV-1
1 Jan 1994
Abstract excerpt
Recently, a family of transcription factors structurally related to Sp1 has been described; thus, more than one activator may bind to the GC boxes present in a number of viral and cellular promoters. We have compared the transactivation potentials of Sp1, Sp3 and Sp4 proteins on the human immunodeficiency virus type 1 (HIV-1) promoter. The long terminal repeat (LTR) of HIV-1 contains three binding sites for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
