Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gain in efficiency from using generalized least squares in the Haseman-Elston test.

Genetic epidemiology - 1 Jan 1995

Single R M, Finch S J

Abstract excerpt

Techniques that test for linkage between a marker and a trait locus based on the regression methods proposed by Haseman and Elston [1972] involve testing a null hypothesis of no linkage by examination of the regression coefficient. Modified Haseman-Elston methods accomplish this using ordinary least squares (OLS), weighted least squares (WLS), in which weights are reciprocals of estimated variances, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Genetic Linkage
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Models, Statistical

Share to Pedigree

Share to Phenotype

Share to Regression Analysis

Source

Identifiers

PMID: 8788027
DOI: 10.1002/gepi.1370120660

Genes

WLS
GLS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gain in efficiency from using generalized least squares in the Haseman-Elston test.PMID 8788027Read ↗

Quantitative trait linkage analysis by generalized estimating equations: unification of variance components and Haseman-Elston regression.Semantic proximity Read ↗

Equivalence between Haseman-Elston and variance-components linkage analyses for sib pairs.Semantic proximity Read ↗

A unified Haseman-Elston method for testing linkage with quantitative traits.Semantic proximity Read ↗

Haseman and Elston revisited.Semantic proximity Read ↗

Gamma regression improves Haseman-Elston and variance components linkage analysis for sib-pairs.Semantic proximity Read ↗

Confidence intervals for heritability via Haseman-Elston regression.Semantic proximity Read ↗

Extension of the Haseman-Elston method to multiple alleles and multiple loci: theory and practice for candidate genes.Semantic proximity Read ↗

Power of a simplified multivariate test for genetic linkage.Semantic proximity Read ↗

Score test for detecting linkage to quantitative traits.Semantic proximity Read ↗

Comparison of Haseman-Elston regression analyses using single, summary, and longitudinal measures of systolic blood pressure.Semantic proximity Read ↗

Transformation of sib-pair values for the Haseman-Elston method.Semantic proximity Read ↗

Extension of the Haseman-Elston regression model to longitudinal data.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.