GAW10: simulated family data for a common oligogenic disease with quantitative risk factors.

doi:10.1002/(SICI)1098-2272(1997)14:6<737::AID-GEPI29>3.0.CO;2-Q

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Article

GAW10: simulated family data for a common oligogenic disease with quantitative risk factors.

Genetic epidemiology - 1 Jan 1997

MacCluer J W, Blangero J, Dyer T D, Speer M C

Abstract excerpt

GAW10 Problem 2 involves a simulated common disease defined by imposing a threshold, T, on a quantitative trait, Q1. Every individual with a value of Q1 > or = T (where T = 40) is defined as affected. Also thought to be associated with the disease as intervening variables are four other quantitat...

Topics

Chromosome Mapping
Computer Simulation
Environment
Female
Genotype
Humans
Male
Models, Genetic
Nuclear Family
Quantitative Trait, Heritable
Risk Factors

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