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Article

GAW10: simulated family data for a common oligogenic disease with quantitative risk factors.

Genetic epidemiology - 1 Jan 1997

MacCluer J W, Blangero J, Dyer T D, Speer M C

Abstract excerpt

GAW10 Problem 2 involves a simulated common disease defined by imposing a threshold, T, on a quantitative trait, Q1. Every individual with a value of Q1 > or = T (where T = 40) is defined as affected. Also thought to be associated with the disease as intervening variables are four other quantitative traits (Q2, Q3, Q4, and Q5) and an environmental factor (EF). Each individual has genotypes for 367 highly...

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Identifiers

PMID: 9433570
DOI: 10.1002/(SICI)1098-2272(1997)14:6<737::AID-GEPI29>3.0.CO;2-Q

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