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Article

Sulfolobus acidocaldarius synthesizes UMP via a standard de novo pathway: results of biochemical-genetic study.

Journal of bacteriology - 1 Mar 1993

Grogan D W, Gunsalus R P

Abstract excerpt

A genetic approach was used to establish the route of UMP biosynthesis in Sulfolobus acidocaldarius, a member of the hyperthermophilic division (the Crenarchaeota) of the Archaea domain. Pyrimidine auxotrophs of S. acidocaldarius DG6 were isolated by direct selection and by brute-force methods. Enzymatic assay of extracts from wild-type S. acidocaldarius, from pyrimidine auxotrophs, and from phenotypic revertants...

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Identifiers

PMID: 8444810
DOI: 10.1128/jb.175.5.1500-1507.1993
PMCID: PMC193238

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