Article
MinK residues line a potassium channel pore.
Neuron - 1 Mar 1996
Wang K W, Tai K K, Goldstein S A
Abstract excerpt
MinK has neither the P region nor signature sequence that characterizes pore-forming subunits of all known K+ channels. A specific minK region has now been identified that affects external blockade by 2 common probes of K+ channel pores. When mutated to cysteine, residues in this region render minK susceptible to covalent blockade by methanethiosulfonate ethylsulfonate and alter reversible inhibition by...
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