Article
Alterations in mitochondrial DNA and enzyme activities in hypertrophied myocardium of stroke-prone SHRS.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jul 1996
Tokoro T, Ito H, Suzuki T
Abstract excerpt
To clarify the pathophysiological alteration of mitochondria in SHRSP hypertrophied heart, mitochondria-related enzyme changes were examined and compared to those in WKY. Furthermore, the structure alteration in mitochondrial DNA (mtDNA) was examined by restriction fragment length polymorphisms (RFLPs). Both isocitrate dehydrogenase (ICDH) and cytochrome c oxidase (COX), which are related to energy production or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.