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Article

HLA-DRB1 polymorphism and susceptibility to multiple sclerosis in the Middle East North Africa region: A systematic review and meta-analysis.

Journal of neuroimmunology - 15 Aug 2018

Mohajer Bahram, Abbasi Nooshin, Pishgar Farhad, Abdolalizadeh Amirhussein, Ebrahimi Hedyeh, Razaviyoun Taraneh, Mohebbi Farnam, Eskandarieh Sharareh, Sahraian Mohammad Ali

Abstract excerpt

This meta-analysis explores association of HLA-DRB1 alleles with MS risk in the Middle-east North Africa (MENA) countries. Divided into two groups of alleles (10 studies, 899 cases/1457 controls) and phenotypes (8 studies, 1,040 cases/1,256 controls), Odds ratios (ORs) of DRB1 distribution in MS subjects were assessed using Cochrane RevMan software. DRB1*15 demonstrated significant association with MS in both...

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PMID: 29957381
DOI: 10.1016/j.jneuroim.2018.06.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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