Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice.

doi:10.1016/0169-328x(94)00251-9

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Article

Enhanced susceptibility of audiogenic seizures in Fyn-kinase deficient mice.

Brain research. Molecular brain research - 1 Feb 1995

Miyakawa T, Yagi T, Taniguchi M, Matsuura H, Tateishi K, Niki H

Abstract excerpt

Mice with a mutation in fyn genes were examined for their susceptibility to acoustically primed audiogenic seizures. Homozygous mutant (fynz/fynz) mice were significantly more likely to have seizures and to show the stronger seizure syndrome (clonus). These results indicate that the susceptibilit...

Topics

Animals
Epilepsy, Tonic-Clonic
Genes
Mice
Models, Genetic
Mutation
Phosphotransferases
Seizures
beta-Galactosidase

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