Article
Histone-like TAFs are essential for transcription in vivo.
Molecular cell - 1 Nov 1998
Michel B, Komarnitsky P, Buratowski S
Abstract excerpt
In yeast, the TBP-associated factors (TAFs) Taf17, Taf60, and Taf61(68) resemble histones H3, H4, and H2B, respectively. To analyze their roles in vivo, conditional alleles were isolated by mutagenizing their histone homology domains. Conditional alleles of TAF17 or TAF60 can be specifically supp...
Topics
- Adaptor Proteins, Signal Transducing
- Alcohol Oxidoreductases
- Alleles
- Amino Acid Sequence
- Aminohydrolases
- Cell Division
- DNA-Binding Proteins
- Enzyme Stability
- Fungal Proteins
- Genes, Fungal
- Histones
- Molecular Sequence Data
- Multienzyme Complexes
- Mutagenesis
- Phenotype
- Pyrophosphatases
- RNA Polymerase II
- RNA, Messenger